Play is backed up at the U.S. Open, as rain delayed and postponed most of Tuesday's matches to create what could be an action-packed Wednesday, if weather permits.

Andy Roddick, who is set to retire at the end of the tournament, could be playing the last match of his career. His fourth-round match with Juan Del Potro was at 6-6 in the first set when it was suspended on Tuesday night.

Del Potro, the only non-Big Three player to win a major in over five years, is favored to win the match, if his balky wrist holds up.

While the home crowd will likely be occupied with the fate of the last American to win a major tournament, the rest of the field is set to play on Wednesday as well, including Roger Federer, Novak Djokovic and Serena Williams.

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