Pettigrew, who has an ankle injury, was one of seven players listed on the report. Pettigrew hasn't played since Week 12 against the Indianapolis Colts. Before that, he hadn't missed a game.
In 13 games this season, Pettigrew has caught 57 passes for 556 yards and three touchdowns.
Pettigrew is in his fourth season in the league, all with the Lions. He has started 54 games over his career. His best season was 2011 when he caught 83 passes for 777 yards and five touchdowns.
Wide receiver Calvin Johnson (knee), safety Louis Delmas (knee), linebacker DeAndre Levy (ankle) and running back Mikel Leshoure (ankle) were at limited at practice Thursday. It was an upgrade for Delmas, who did not practice on Wednesday.
Safety Don Carey (knee) and cornerback Chris Houston (hamstring) were also listed on the injury report, but both were full participants.
The Lions (4-10) play the Atlanta Falcons (12-2) Saturday at 8:30 p.m. ET.