Carl Edwards won for the third time in the last five races, winning Sunday's Kobalt Tools 400 for his second Las Vegas victory.
Tony Stewart, who led the most laps, finished second, followed by Juan Pablo Montoya, Marcos Ambrose, and Ryan Newman.
It is the 19th career win for Edwards and his 14th on an intermediate track.
It was a short, frustrating day for Kyle Busch, who entered the race as the point leader. The driver of the No. 18 Toyota had a tire go flat as he was running second to Stewart. Two cautions later, his engine erupted in plume of smoke and fire, relegating him to a miserable 38th place finish.
Jeff Gordon, last week's winner, brought out the race's final caution with a hard crash in turn four and finished 36th.
Polesitter Matt Kenseth cut a tire on the restart from the first caution of the day, a spin by Robby Gordon, and lost two laps. He finally got back onto the lead lap after Gordon's crash, but was never a factor in a race many had pegged him as the favorite to win, finishing 11th.